Bufotalins meaning

Bufotalins are a group of toxic steroid compounds found in the skin glands of certain toads.


Bufotalins definitions

Word backwards snilatofub
Part of speech Bufotalins is a noun.
Syllabic division bu-fo-ta-lins
Plural The plural form of the word "bufotalins" is bufotalides.
Total letters 10
Vogais (4) u,o,a,i
Consonants (6) b,f,t,l,n,s

Bufotalins: An Overview

Bufotalins are a group of chemical compounds found in the skin secretions of certain species of toads, particularly in the genus Bufo. These compounds are known for their potent biological activities and have been studied for their potential pharmaceutical uses. Bufotalins belong to a class of compounds called bufadienolides, which are steroid-like substances with a wide range of pharmacological effects.

Chemical Structure and Properties of Bufotalins

Bufotalins are characterized by a unique chemical structure that includes a steroid nucleus with a lactone ring. This structure is responsible for their biological activities, which include cardiotonic, antitumor, and anti-inflammatory effects. Some bufotalins have been found to inhibit the growth of cancer cells and induce apoptosis, making them potential candidates for cancer treatment.

Pharmacological Effects of Bufotalins

Research has shown that bufotalins have a variety of pharmacological effects, including positive inotropic and chronotropic effects on the heart. These compounds have been used in traditional Chinese medicine for centuries to treat heart conditions and other ailments. Additionally, bufotalins have shown promising results in preclinical studies for their potential anti-cancer and anti-inflammatory properties.

Therapeutic Potential of Bufotalins

Due to their diverse pharmacological effects, bufotalins have gained significant attention in the field of drug discovery. Researchers are exploring the potential therapeutic applications of these compounds in the treatment of cardiovascular diseases, cancer, and inflammatory conditions. However, further studies are needed to fully understand the mechanisms of action and potential side effects of bufotalins in humans.

Overall, bufotalins are fascinating compounds with a wide range of pharmacological effects. As research in this field continues to advance, these compounds may hold promise for the development of novel therapies for various diseases. With their unique chemical structure and potent biological activities, bufotalins are an intriguing area of study in the field of natural products and drug discovery.


Bufotalins Examples

  1. Bufotalins are a class of chemical compounds found in the skin secretion of certain toads.
  2. The bufotalins extracted from toads have been used historically in traditional Chinese medicine.
  3. Research is ongoing to investigate the pharmacological properties of bufotalins.
  4. Some studies suggest that bufotalins may have anti-tumor effects.
  5. Bufotalins are known to have cardiotoxic effects if ingested in large quantities.
  6. The synthesis of bufotalins in a laboratory setting is challenging due to their complex structure.
  7. Certain species of toads produce bufotalins as a defense mechanism against predators.
  8. The mechanism of action of bufotalins in the human body is not fully understood.
  9. Bufotalins have been studied for their potential use in treating certain types of cancer.
  10. The concentration of bufotalins in toad secretions can vary depending on environmental factors.


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  • Updated 30/06/2024 - 22:40:05