Cholestasis meaning

Cholestasis is a condition characterized by the decreased or blocked flow of bile from the liver.


Cholestasis definitions

Word backwards sisatselohc
Part of speech Noun
Syllabic division cho-les-ta-sis
Plural The plural of the word cholestasis is cholestatses.
Total letters 11
Vogais (4) o,e,a,i
Consonants (5) c,h,l,s,t

Understanding Cholestasis

Cholestasis is a condition that occurs when the flow of bile from the liver is impaired. Bile is a digestive fluid that helps to break down fats in the small intestine. When bile cannot flow properly, it builds up in the liver and can lead to liver damage.

Symptoms and Causes

Cholestasis can present with symptoms such as itching, dark urine, pale stools, and jaundice (yellowing of the skin and eyes). Pregnant women may develop a specific type of cholestasis known as obstetric cholestasis. This condition typically occurs in the third trimester and can be associated with severe itching.

Diagnosis and Treatment

Diagnosing cholestasis often involves blood tests to measure levels of liver enzymes and bile acids. Imaging tests such as ultrasounds and MRIs may also be used to assess the liver and bile ducts. Treatment for cholestasis typically focuses on relieving symptoms and addressing the underlying cause. Medications may be prescribed to help improve bile flow, and in some cases, surgical intervention may be necessary.

Complications and Outlook

If left untreated, cholestasis can lead to complications such as liver damage, cirrhosis, and an increased risk of gallstones. It is essential for individuals experiencing symptoms of cholestasis to seek medical attention promptly. With proper management and treatment, the outlook for cholestasis can be positive, especially if the condition is diagnosed and treated early.


Cholestasis Examples

  1. Pregnancy can sometimes lead to intrahepatic cholestasis, a liver condition that causes itching and jaundice.
  2. Obstructive cholestasis occurs when bile flow from the liver is blocked, leading to a buildup of bile acids.
  3. Cholestasis of the liver can result in elevated levels of bilirubin in the bloodstream.
  4. A common symptom of cholestasis is dark urine due to the presence of excess bilirubin.
  5. Patients with cholestasis may experience fatigue and malaise as a result of impaired liver function.
  6. Cholestasis can be diagnosed through blood tests that measure levels of liver enzymes and bilirubin.
  7. Treatment for cholestasis may involve medications to reduce bile acid levels and relieve symptoms.
  8. In some cases, cholestasis may require a liver transplant if the condition is severe and does not improve with other treatments.
  9. Cholestasis can lead to complications such as liver failure, so prompt diagnosis and management are essential.
  10. Research is ongoing to better understand the underlying mechanisms of cholestasis and develop new treatments for the condition.


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  • Updated 15/05/2024 - 21:22:17